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. 1994 Feb;24(2):151-4.
doi: 10.1111/j.1365-2559.1994.tb01294.x.

Gastric epithelial atypia complicating hepatic arterial infusion chemotherapy

W S Kwee  1 , J A Wils, J Schlangen, C M Nuyens, J W Arends
Affiliations

Gastric epithelial atypia complicating hepatic arterial infusion chemotherapy

W S Kwee et al. Histopathology. 1994 Feb.

Abstract

Severe gastric lesions developed in five patients during hepatic arterial infusion chemotherapy employing 5-fluorouracil plus either leucovorin or mitomycin C. Ulceration with marked epithelial atypia was observed with striking structural distortion and cellular pleomorphism of the affected gastric mucosa. These features should be considered to be a complication of such treatment and should not be misinterpreted as malignancy.

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