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Review
. 1994 Jan;61(1):51-6.

Deoxyspergualin--a novel immunosuppressant

R M Jindal  1 , M A Tepper, K Soltys, S I Cho
Affiliations
  • PMID: 8183294
Review

Deoxyspergualin--a novel immunosuppressant

R M Jindal et al. Mt Sinai J Med. 1994 Jan.

Abstract

DSG appears to have a unique, although as yet undefined, mechanism of action and may be a useful immunosuppressive agent. Because DSG is effective in reducing preformed antibodies in the xenograft situation, it may have a significant advantage in ABO-incompatible grafts in transplant recipients with high panel-reactive antibodies. Most important, DSG may have a definitive role in immunosuppressive therapy for pancreatic grafts.

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