Molecular cloning of an Entamoeba histolytica gene encoding a putative mos family serine/threonine-kinase

Abstract

Molecular cloning techniques were used to isolate an ameba gene encoding a putative 33-kDa serine/thyronine-kinase. The open reading frame of this gene, called Ehmfk1 for E. histolytica mos family kinase, shows a 24% positional identity with the human proto-oncogene mos, including 32 of 33 amino acids conserved in other serine/threonine-kinases.