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Case Reports
. 1994;424(3):327-30.
doi: 10.1007/BF00194619.

Early malignant histiocytosis of the intestine: an autopsy report

K Ohshima  1 , K Yoshitake, H Ugaeri, M Kikuchi, S Yoneda
Affiliations
Case Reports

Early malignant histiocytosis of the intestine: an autopsy report

K Ohshima et al. Virchows Arch. 1994.

Abstract

A 63-year-old man with malignant histiocytosis of the intestine died 3 days after gastrectomy for early gastric adenocarcinoma. Malignant histiocytosis of the intestine was unexpectedly found at autopsy. The intestine was thickened with mucosal erosions. Histologically, a few atypical large histiocyte-like cells were found in focal aggregates in the mucosa. These large cells expressed the T-cell antigen and monoclonality was demonstrated by the polymerase chain reaction showing variable-joining segment rearrangement in the T-cell receptor delta-chain gene. Malignant histiocytosis of the intestine was thus diagnosed.

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