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. 1994 Jan-Feb;17(1):12-6.

Prophylactic endovascular radiotherapy to prevent intimal hyperplasia after stent implantation in femoropopliteal arteries

D Liermann  1 , H D Bottcher, J Kollath, B Schopohl, G Strassmann, E P Strecker, K H Breddin
Affiliations
  • PMID: 8187126

Prophylactic endovascular radiotherapy to prevent intimal hyperplasia after stent implantation in femoropopliteal arteries

D Liermann et al. Cardiovasc Intervent Radiol. 1994 Jan-Feb.

Abstract

Purpose: Recurrent stenosis or occlusion by intimal hyperplasia occurs in up to 40% of patients with tantalum stent implantations in femoropopliteal arteries and greatly restricts their usefulness. We evaluated the effect of prophylactic endovascular radiotherapy on stenosed/occluded stents.

Methods: We investigated prophylactic endovascular radiotherapy with a surface dose of 12 Gy using an iridium 192 source as a means to reduce or eliminate recurrent stenosis in 4 patients with stenosed/occluded stents, 6-8 months after the original implantation. Confirmatory diagnostic atherectomy, PTA or laser recanalization and endovascular radiotherapy were performed.

Results: None of the four has developed recurrent obstruction within 23 to 30 months after this treatment, which up to now shows no short-term or long-term complications.

Conclusion: We conclude that this limited experience is promising enough to warrant further study.

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