Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Apr;276(1):209-12.
doi: 10.1007/BF00354801.

Synthesis of platelet-derived growth factor by cells of splenic red pulp in normal rats

R E Dill  1 , E K Miller, B J Dyer, A M Iacopino
Affiliations

Synthesis of platelet-derived growth factor by cells of splenic red pulp in normal rats

R E Dill et al. Cell Tissue Res. 1994 Apr.

Abstract

A population of cells in the spleens of normal rats was found to contain platelet-derived growth factor (PDGF) B chain mRNA. These cells were found predominantly in the red pulp and nuclear morphology of some was consistent with that of macrophages. Similar cells were also shown by immunocytochemical staining to contain PDGF-AB/BB. These PDGF-positive cells were also found almost exclusively in the red pulp. It has been suggested by others that PDGF plays an important role in the function of the lymphohemopoietic microenvironment.

PubMed Disclaimer

References

    1. Nature. 1985 Aug 22-28;316(6030):748-50 - PubMed
    1. J Comp Neurol. 1987 Aug 1;262(1):125-40 - PubMed
    1. J Histochem Cytochem. 1981 Apr;29(4):577-80 - PubMed
    1. Leuk Res. 1985;9(4):427-34 - PubMed
    1. Blood. 1989 Jul;74(1):303-11 - PubMed

Publication types

Substances