Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1994 Apr;52(4):969-73.

[Thyrotropin receptor is expressed in non-thyroid tissues]

[Article in Japanese]
T Endo  1 , T Onaya
Affiliations
  • PMID: 8196188
Review

[Thyrotropin receptor is expressed in non-thyroid tissues]

[Article in Japanese]
T Endo et al. Nihon Rinsho. 1994 Apr.

Abstract

We have obtained TSH-R cDNA fragments from rat retro-orbital tissues and adipose tissue as well as FRTL5 cells by polymerase chain reaction methods. Nucleotide sequence of the non-thyroid cDNA was identical to that of the thyroid. Northern blot analysis has revealed that extremely high amount of TSH-R mRNA exist in the adipose tissue. TSH-R peptide antibody produced in rabbit, which stained recombinant TSH-R as 104 and 100 kDa proteins, also recognized the same M.W. bands in the adipose tissue and the retro-orbital tissues. These results suggest that TSH-R is expressed even in non-thyroid tissues.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

LinkOut - more resources