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Case Reports
. 1994 Feb;86(2):413-4.
doi: 10.1111/j.1365-2141.1994.tb04756.x.

Parvovirus B19-associated haemophagocytic syndrome with prominent neutrophilia

H Tsuda  1 , Y Maeda, K Nakagawa, M Nakayama, H Nishimura, A Ishihara, H Miyayama
Affiliations
Case Reports

Parvovirus B19-associated haemophagocytic syndrome with prominent neutrophilia

H Tsuda et al. Br J Haematol. 1994 Feb.

Abstract

We describe a patient with both haemophagocytic syndrome and acute myocarditis probably associated with parvovirus B19 infection. The patient had a marked neutrophilia instead of neutropenia more usually observed in virus-associated haemophagocytic syndrome (VAHS). Endogenous serum concentrations of macrophage colony-stimulating factor (M-CSF), granulocyte colony-stimulating factor (G-CSF), and tumour necrosis factor-alpha (TNF-alpha) were higher than normal, suggesting that these cytokines may be involved in the genesis of the observed syndrome.

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