Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Jan-Feb;12(1):30-40.
doi: 10.1007/BF02581110.

Transplantation of isologous islets of Langerhans in diabetic rats

D Lorenz, K D Rosenbaum, J Petermann, M Ziegler, R Beckert, A Dorn

Transplantation of isologous islets of Langerhans in diabetic rats

D Lorenz et al. Acta Diabetol Lat. 1975 Jan-Feb.

Abstract

Isologous isolated islets of Langerhans were transplanted into the peritoneum and, via the portal vein, into the liver of diabetic rats. In both groups almost normal blood glucose and serum insulin levels were achieved for a period of three months. Glucose tolerance tests were markedly improved. Morphological examination of the transplanted islets and immunohistochemical tests for insulin and glucagon showed the liver to be a more suitable site for islet grafting than the peritoneum.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Endocrinology. 1957 Mar;60(3):359-67 - PubMed
    1. Diabetologia. 1973 Dec;9(6):486-91 - PubMed
    1. Surgery. 1972 Aug;72(2):175-86 - PubMed
    1. Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1968;11(4):585-90 - PubMed
    1. Diabetes. 1967 Jan;16(1):35-9 - PubMed