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Clinical Trial
. 1994 Jun 6;160(11):701-4.

Lack of efficacy of single-dose prednisolone in moderately severe asthma

L Ho  1 , L I Landau, P N Le Souëf
Affiliations
  • PMID: 8202005
Clinical Trial

Lack of efficacy of single-dose prednisolone in moderately severe asthma

L Ho et al. Med J Aust. .

Abstract

Objective: To assess the effectiveness of single-dose prednisolone in reducing the length of illness and hospital stay in children admitted with moderately severe asthma.

Design: A randomised, double-blind, controlled trial of a single dose of prednisolone in 64 children presenting with an acute attack of asthma with arterial oxygen saturation less than 93%.

Results: No significant differences in the rate of recovery of oxygen saturation, lung function measurements or duration of hospital stay were found.

Conclusions: This study failed to confirm the benefit of a single dose of prednisolone in the management of children with acute severe asthma.

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