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. 1976 Jun;9(6):945-50.
doi: 10.1128/AAC.9.6.945.

Enzymatic modification of aminoglycoside antibiotics: a new 6'-N-acetylating enzyme from a Pseudomonas aeruginosa isolate

M Haas, S Biddlecome, J Davies, C E Luce, P J Daniels

Enzymatic modification of aminoglycoside antibiotics: a new 6'-N-acetylating enzyme from a Pseudomonas aeruginosa isolate

M Haas et al. Antimicrob Agents Chemother. 1976 Jun.

Abstract

We describe an aminoglycoside 6'-N-acetyltransferase, isolated from Pseudomonas aeruginosa, that exhibits a novel substrate profile characterized by markedly reduced activity towards butirosin and amikacin.

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References

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    1. Biochimie. 1974;56(6-7):893-7 - PubMed
    1. Methods Enzymol. 1975;43:611-28 - PubMed
    1. J Org Chem. 1974 May 31;39(11):1451-7 - PubMed
    1. Antimicrob Agents Chemother. 1973 Jul;4(1):6-10 - PubMed

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