Comparative Study
doi: 10.1016/s0140-6736(78)92341-3.
Selective inactivation of vitamin B12 in rats by nitrous oxide
- PMID: 82036
- DOI: 10.1016/s0140-6736(78)92341-3
Item in Clipboard
Comparative Study
Selective inactivation of vitamin B12 in rats by nitrous oxide
Lancet.
.
Abstract
Exposure of rats to nitrous oxide rapidly inactivated the cytosol enzyme, methionine synthetase, but the mitochondrial enzyme, methylmalonyl CoA mutase, seemed to be unaffected, although both enzymes require vitamin B12.
Similar articles
-
Effect of dietary and nitrous oxide-induced vitamin B-12 deficiency on uptake of 5-methyltetrahydrofolate by isolated rat hepatocytes.J Nutr. 1980 Feb;110(2):223-30. doi: 10.1093/jn/110.2.223. J Nutr. 1980. PMID: 6101617
-
Effect of nitrous oxide inactivation of vitamin B12-dependent methionine synthetase on the subcellular distribution of folate coenzymes in rat liver.Arch Biochem Biophys. 1989 May 1;270(2):729-33. doi: 10.1016/0003-9861(89)90556-0. Arch Biochem Biophys. 1989. PMID: 2705787
-
Nitrous oxide, vitamin B12 deficiency and the methyl folate trap.Nutr Rev. 1982 May;40(5):152-4. doi: 10.1111/j.1753-4887.1982.tb05294.x. Nutr Rev. 1982. PMID: 6124918 Review. No abstract available.
-
Methylmalonyl-CoA mutase (EC 5.4.99.2) and methionine synthetase (EC 2.1.1.13) in the tissues of cobalt-vitamin B12 deficient sheep.Br J Nutr. 1990 Nov;64(3):721-32. doi: 10.1079/bjn19900074. Br J Nutr. 1990. PMID: 1979918
-
Cobalamins and nitrous oxide: a review.J Clin Pathol. 1980 Oct;33(10):909-16. doi: 10.1136/jcp.33.10.909. J Clin Pathol. 1980. PMID: 6107306 Free PMC article. Review. No abstract available.
Cited by
-
Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients.Cancer Chemother Pharmacol. 2016 Nov;78(5):1093-1096. doi: 10.1007/s00280-016-3153-0. Epub 2016 Sep 22. Cancer Chemother Pharmacol. 2016. PMID: 27659182 Free PMC article.
-
Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.Circ Cardiovasc Genet. 2009 Apr;2(2):142-50. doi: 10.1161/CIRCGENETICS.108.829804. Circ Cardiovasc Genet. 2009. PMID: 20031578 Free PMC article.
-
Megaloblastic anemia--etiology and management.Indian J Pediatr. 1987 May-Jun;54(3):343-53. doi: 10.1007/BF02748918. Indian J Pediatr. 1987. PMID: 3301655 Review. No abstract available.
-
Megaloblastic anaemia, cobalamin, and folate.J Clin Pathol. 1987 Sep;40(9):978-84. doi: 10.1136/jcp.40.9.978. J Clin Pathol. 1987. PMID: 3312306 Free PMC article. Review.
-
Effect of cobalamin inactivation on folate-dependent transformylases involved in purine synthesis in rats.Biochem J. 1985 Apr 1;227(1):67-71. doi: 10.1042/bj2270067. Biochem J. 1985. PMID: 3994693 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
