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Comparative Study
. 1976 Apr 26;282(16):1567-70.

[Deformation and orientation of sickle erythrocytes submitted to shearing forces]

[Article in French]
M Bessis, N Mohandas
  • PMID: 820461
Comparative Study

[Deformation and orientation of sickle erythrocytes submitted to shearing forces]

[Article in French]
M Bessis et al. C R Acad Hebd Seances Acad Sci D. .

Abstract

Blood from patients with homozygous sickle cell anemia gives a "cross shaped" diffraction pattern, when submitted to shear stresses in the Ektacytometer. This pattern, which seems to be specific to these cells, is due to the existence of two populations of elliptical cells: one population (normal, deformable cells) aligned parallel to the direction of the flow, and the other (abnormal, rigid cells) perpendicular to the direction of the flow.

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