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Review
. 1993 Dec;101 Suppl 4(Suppl 4):59-66.
doi: 10.1289/ehp.93101s459.

Basic problems in interaction assessment

S Greenland  1
Affiliations
Review

Basic problems in interaction assessment

S Greenland. Environ Health Perspect. 1993 Dec.

Abstract

This paper reviews problems with the definition and estimation of interactions in epidemiologic studies. Methods for modeling interactions and dose-response also are reviewed, and references to more detailed literature are provided. Concepts are illustrated in the context of evaluating the joint effects of household radon exposure and environmental tobacco smoke.

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