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. 1994 Jun 10;143(2):285-7.
doi: 10.1016/0378-1119(94)90112-0.

A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII

C H Yeh  1 , A J Shatkin
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A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII

C H Yeh et al. Gene. .

Abstract

A 1.2-kb cDNA clone isolated from a HeLa cell library contains an open reading frame encoding a new protein (p21) of 21 kDa that is approx. 48% similar to members of the eukaryotic transcription elongation factor SII (TFIIS) family. The deduced amino-acid sequence of p21 indicates that it is hydrophilic, basic and contains nuclear localization signals, as well as multiple consensus phosphorylation sites.

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