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. 1993;86(2):172-5.
doi: 10.1007/BF00334884.

Primary central white matter degeneration in old dogs

I Ferrer  1 , M Pumarola, R Rivera, M J Zújar, F Cruz-Sánchez, A Vidal
Affiliations

Primary central white matter degeneration in old dogs

I Ferrer et al. Acta Neuropathol. 1993.

Abstract

Degeneration of the central white matter is described in old dogs. The presence of ubiquitin-immunoreactive free granules and intracytoplasmic globules in glial cells and macrophages, together with galacerebroside-immunoreactive precipitates and lipofusion storage, point to the likelihood of a primary myelin degeneration with deposits of non-degraded ubiquitin-protein conjugates and complex galactolipids.

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