Primary central white matter degeneration in old dogs
- PMID: 8213071
- DOI: 10.1007/BF00334884
Primary central white matter degeneration in old dogs
Abstract
Degeneration of the central white matter is described in old dogs. The presence of ubiquitin-immunoreactive free granules and intracytoplasmic globules in glial cells and macrophages, together with galacerebroside-immunoreactive precipitates and lipofusion storage, point to the likelihood of a primary myelin degeneration with deposits of non-degraded ubiquitin-protein conjugates and complex galactolipids.
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