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Case Reports
. 1993 Oct;88(10):1756-8.

Exacerbation of psoriasis due to interferon-alpha treatment of chronic active hepatitis

M J Georgetson  1 , J C Yarze, A T Lalos, G F Webster, P Martin
Affiliations
  • PMID: 8213720
Case Reports

Exacerbation of psoriasis due to interferon-alpha treatment of chronic active hepatitis

M J Georgetson et al. Am J Gastroenterol. 1993 Oct.

Abstract

Interferon-alpha is an immune modulating drug which is indicated for the treatment of chronic viral hepatitis B and C. Several previous reports have suggested an association between treatment of patients with interferon-alpha and the development or exacerbation of autoimmune diseases. We report two patients with chronic viral hepatitis in whom treatment with interferon-alpha was associated with dramatic worsening of previously diagnosed psoriasis, necessitating discontinuation of the drug.

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