Clinical research, prophylaxis, therapy, and care for HIV disease in Africa
- PMID: 8214225
- PMCID: PMC1694848
- DOI: 10.2105/ajph.83.10.1385
Clinical research, prophylaxis, therapy, and care for HIV disease in Africa
Abstract
By the end of the century, citizens of resource-poor countries will constitute 90% of the world's human immunodeficiency virus (HIV)-infected people. Clinical management of such persons in developing countries has been neglected; most AIDS research has concentrated on epidemiology, and donor agencies have generally invested in the prevention of HIV infection. The heavy burden of HIV disease in Africa requires that care for AIDS be addressed, and prevention and care should be seen as interrelated. Prevention and treatment of tuberculosis, the commonest severe infection in persons with AIDS in Africa, illustrate this interrelationship. We outline priorities for applied research on the management of HIV disease in a resource-poor environment, and discuss prophylaxis, therapy for opportunistic diseases, terminal care, and use of antiretroviral therapy. Research should define the standard of care that can realistically be demanded for HIV disease in a resource-poor environment. Research and public health programs for AIDS in developing countries must address AIDS care and attempt to reduce the widening gap between interventions available for HIV-infected persons in different parts of the world.
Comment in
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HIV and AIDS in Africa. 1. Assisting those in the early stages of HIV infection.Am J Public Health. 1994 Jul;84(7):1178; author reply 1179. doi: 10.2105/ajph.84.7.1178. Am J Public Health. 1994. PMID: 8017550 Free PMC article. No abstract available.
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HIV and AIDS in Africa. Research priorities should not be limited to prophylaxis.Am J Public Health. 1994 Jul;84(7):1178-9. doi: 10.2105/ajph.84.7.1178-a. Am J Public Health. 1994. PMID: 8017551 Free PMC article. No abstract available.
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When ideals meet reality--the global challenge of HIV/AIDS.Am J Public Health. 1993 Oct;83(10):1383-4. doi: 10.2105/ajph.83.10.1383. Am J Public Health. 1993. PMID: 8214224 Free PMC article. No abstract available.
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