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. 1976 Mar 15;154(3):783-5.
doi: 10.1042/bj1540783.

Effect on uridine diphosphate glucuronyltransferase activity of depleting and restoring phospholipids to guinea-pig liver microsomal preparations

C S Berry, M Caldecourt, T Hallinan

Effect on uridine diphosphate glucuronyltransferase activity of depleting and restoring phospholipids to guinea-pig liver microsomal preparations

C S Berry et al. Biochem J. .

Abstract

Phospholipid depletion substantially inhibited the maximum demonstrable activities of the forward (glucuronidation) and reverse reactions of UDP-glucuronyltransferase towards p-nitrophenol in guinea-pig liver microsomal preparations. Dispersions of liver phospholipids restored activity, whereas non-phospholipid amphipaths failed to do so effectively. These results suggest that the system is probably phospholipid-dependent rather than conformationally constrained by phospholipids.

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References

    1. Arch Biochem Biophys. 1967 Apr;120(1):198-203 - PubMed
    1. Biochim Biophys Acta. 1972 Apr 7;268(1):61-9 - PubMed
    1. J Biol Chem. 1972 May 25;247(10):2979-88 - PubMed
    1. J Biol Chem. 1971 Aug 10;246(15):4649-56 - PubMed
    1. Eur J Biochem. 1973 Sep 21;38(1):59-63 - PubMed