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. 1976 Aug;25(2):347-51.

Cytotoxic activity of human lymphocyte plasma membranes

J Ferluga, G J Friou, A C Allison

Cytotoxic activity of human lymphocyte plasma membranes

J Ferluga et al. Clin Exp Immunol. 1976 Aug.

Abstract

Plasma membrane fractions isolated from normal human peripheral blood lymphocytes have considerable cytolytic activity towards a cultured human lymphoblast cell line and mouse mastocytoma cells. Other subcellular fractions, including lysosomes, have low cytolytic activity. It is suggested that this cytotoxic potential in lymphocyte plasma membranes is normally latent but can be activated by prolonged and intimate contact with target cell plasma membranes.

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References

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