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Clinical Trial
. 1976:33:93-7.

Controlled field trials of killed oral typhoid and paratyphoid B vaccines and cell-free, chemical aerosol typhoid vaccine

L B Hejfec, L A Levina, L B Salmin, A A Antonova, L S Segal, M L Kuzminova, K M Slavina, A V Vasileva
  • PMID: 821803
Clinical Trial

Controlled field trials of killed oral typhoid and paratyphoid B vaccines and cell-free, chemical aerosol typhoid vaccine

L B Hejfec et al. Dev Biol Stand. 1976.

Abstract

Three controlled field trials were carried out. One of them (1963) showed that an aerosol with cell-free, chemical typhoid vaccine did not protect vaccinees from the disease. The other trials (1964 and 1965) assessing the efficacy of killed oral typhoid vaccine revealed a short term (up to 3 months) protective effect. In the trial of oral paratyphoid B vaccine no statistically significant difference in morbidity in the test and control groups was observed due to the small number of cases.

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