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Case Reports
. 1993 Sep;11(1-2):149-52.
doi: 10.3109/10428199309054744.

Translocation t(1;19) in acute lymphoblastic leukemia patients with cytological presentation simulating L3-ALL (Burkitt-like)

M Lessard  1 , O Fenneteau, D Sainty, F Valensi, E MacIntyre, G Flandrin
Affiliations
Case Reports

Translocation t(1;19) in acute lymphoblastic leukemia patients with cytological presentation simulating L3-ALL (Burkitt-like)

M Lessard et al. Leuk Lymphoma. 1993 Sep.

Abstract

The t(1;19) in B-lineage ALL is classically associated with a FAB L1/L2 phenotype and the expression of cIg. Recent reports have demonstrated immuno-phenotypic and molecular heterogeneity among cases demonstrating apparently identical karyotypic abnormalities. We report 5 cases of t(1;19) with cytological features resembling an L3 (Burkitt-like) phenotype, suggesting that accurate assessment of these cases requires detailed correlation of cytological, immunological and molecular characteristics.

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