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. 1976 Sep 1;144(3):852-7.
doi: 10.1084/jem.144.3.852.

Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells

J W Goding, J E Layton

Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells

J W Goding et al. J Exp Med. .

Abstract

Double fluorescence studies indicated that most mature lymphocytes of 11-52-wk-old mice possess both IgM and IgD-like surface immunoglobulins, while spleen cells from neonatal mice possess surface IgM only. These molecules cap independently with class-specific antisera, but co-cap when capping is induced by antigen. It is proposed that the two heavy chains on individual lymphocytes possess similar or identical antigen-combining sites.

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References

    1. J Immunol. 1973 Oct;111(4):1295-8 - PubMed
    1. Scand J Immunol. 1974;3(6):841-6 - PubMed
    1. Nature. 1974 Dec 13;252(5484):600-2 - PubMed
    1. J Exp Med. 1976 Mar 1;143(3):511-28 - PubMed
    1. J Exp Med. 1973 Apr 1;137(4):1024-30 - PubMed

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