Case-control study of prenatal ultrasonography exposure in children with delayed speech
- PMID: 8221427
- PMCID: PMC1485930
Case-control study of prenatal ultrasonography exposure in children with delayed speech
Abstract
Objective: To determine whether there is an association between prenatal ultrasound exposure and delayed speech in children.
Design: Case-control study.
Setting: Network of community physicians affiliated with the Primary Care Research Unit, University of Calgary.
Subjects: Thirty-four practitioners identified 72 children aged 24 to 100 months who had undergone a formal speech-language evaluation and were found to have delayed speech of unknown cause by a speech-language pathologist. For each case subject the practitioners found two control subjects matched for sex, date of birth, sibling birth order and associated health problems.
Main outcome measures: Rates of prenatal ultrasound exposure and delayed speech.
Results: The children with delayed speech had a higher rate of ultrasound exposure than the control subjects. The findings suggest that a child with delayed speech is about twice as likely as a child without delayed speech to have been exposed to prenatal ultrasound waves (odds ratio 2.8, 95% confidence limit 1.5 to 5.3; p = 0.001).
Conclusion: An association between prenatal ultrasonography exposure and delayed speech was found. If there is no obvious clinical indication for diagnostic in-utero ultrasonography, physicians might be wise to caution their patients about the vulnerability of the fetus to noxious agents.
Comment in
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Studying delayed speech.CMAJ. 1994 Mar 1;150(5):647. CMAJ. 1994. PMID: 8179670 Free PMC article. No abstract available.
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Studying delayed speech.CMAJ. 1994 Mar 1;150(5):647-8. CMAJ. 1994. PMID: 8313281 Free PMC article. No abstract available.
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Studying delayed speech.CMAJ. 1994 Mar 1;150(5):648-9. CMAJ. 1994. PMID: 8313282 Free PMC article. No abstract available.
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