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. 1976 Aug 10;147(1):13-21.
doi: 10.1007/BF00337930.

Nucleoside auxotrophy in Drosophila: an autosomal locus yielding mutants supplementable by purine and pyrimidine ribonucleosides

F N Naguib, D Nash

Nucleoside auxotrophy in Drosophila: an autosomal locus yielding mutants supplementable by purine and pyrimidine ribonucleosides

F N Naguib et al. Mol Gen Genet. .

Abstract

Two allelic auxotrophic mutants at a locus close to the bw locus (2-104.5) of Drosophila melanogaster are described. The mutants respond to dietary ribonucleosides (uridine, cytidine, adenosine, guanosine and inosine) but less well to bases or pyrimidine precursors. This phenotype is unique to these mutants. We suggest that the mutants are defective in phosphoribosyl pyrophosphate biosynthesis.

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References

    1. Biochemistry. 1973 Oct 9;12(21):4039-51 - PubMed
    1. Hereditas. 1974;78(2):157-68 - PubMed
    1. Hereditas. 1973;73(1):11-6 - PubMed
    1. Nature. 1975 Jun 26;255(5511):738-40 - PubMed
    1. Z Indukt Abstamm Vererbungsl. 1956;87(3):482-92 - PubMed

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