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. 1976 Jun;13(6):1559-62.
doi: 10.1128/iai.13.6.1559-1562.1976.

Adjuvant effects of diethylaminoethyl-dextran

W E Houston, C L Crabbs, R J Kremer, J W Springer

Adjuvant effects of diethylaminoethyl-dextran

W E Houston et al. Infect Immun. 1976 Jun.

Abstract

Diethylaminoethyl-dextran exhibited a significant effect on the primary immune response of rhesus monkeys to formalin-inactivated Venezuelan equine encephalomyelitis virus vaccine (IVEE). Antibody formed to IVEE and adjuvant followed a classic immunoglobulin M-immunoglobulin G pattern; however, as compared with vaccine alone, use of this adjuvant with IVEE reduced the time required for onset of immunoglobulin G synthesis.

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