doi: 10.1055/s-2008-1071546.
Vigabatrin in the treatment of infantile spasms
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- PMID: 8232783
- DOI: 10.1055/s-2008-1071546
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Vigabatrin in the treatment of infantile spasms
Neuropediatrics.
1993 Aug.
Abstract
The anti-epileptic effect of vigabatrin as a first choice therapy was investigated in 6 children suffering from infantile spasms (IS). All 6 children showed a reduction in seizure frequency. Three children became seizure-free within a period of 2 weeks. Because our results suggest "an all or nothing phenomenon", a period of 2 weeks may be sufficient to evaluate the efficacy of vigabatrin in untreated infants suffering from IS. We suggest to use vigabatrin as a first choice anti-epileptic drug in infants with IS.
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