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. 1993 Nov 1;90(21):10320-4.
doi: 10.1073/pnas.90.21.10320.

Split decomposition: a technique to analyze viral evolution

J Dopazo  1 , A Dress, A von Haeseler
Affiliations

Split decomposition: a technique to analyze viral evolution

J Dopazo et al. Proc Natl Acad Sci U S A. .

Abstract

A clustering technique allowing a restricted amount of overlapping and based on an abstract theory of coherent decompositions of finite metrics is used to analyze the evolution of foot-and-mouth disease viruses. The emerging picture is compatible with the existence of viral populations with a quasispecies structure and illustrates various forms of evolution of this virus family. In addition, it allows the correlation of these forms with geographic occurrence.

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