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Case Reports
. 1993;149(3):175-6.

[Effects of the stimulation of the subthalamic nucleus in Parkinson disease]

[Article in French]
P Pollak  1 , A L Benabid, C Gross, D M Gao, A Laurent, A Benazzouz, D Hoffmann, M Gentil, J Perret
Affiliations
  • PMID: 8235208
Case Reports

[Effects of the stimulation of the subthalamic nucleus in Parkinson disease]

[Article in French]
P Pollak et al. Rev Neurol (Paris). 1993.

Abstract

In Parkinson's disease, experimental studies favour a neuronal hyperactivity of the subthalamic nucleus. We carried out a subthalamic nucleus electrical stimulation in a patient aged 51, suffering for 8 years from a severe akineto-rigid form of Parkinson's disease, complicated with an on-off effect. Stereotaxic surgery was done under local anaesthesia on one side. Within the theoretical target, a 130 Hz stimulation induced akinesia alleviation mainly on the contralateral limbs. No abnormal movement was noticed. Then a long-term quadripolar DBS Medtronic electrode was inserted in that area. The study of the effects of chronic stimulation is in progress to determine the best temporal and electrical stimulation variables.

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