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Review
. 1993 Sep;9(9):310-7.
doi: 10.1016/0168-9525(93)90249-h.

Requiem for distributive segregation: achiasmate segregation in Drosophila females

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Review

Requiem for distributive segregation: achiasmate segregation in Drosophila females

R S Hawley et al. Trends Genet. 1993 Sep.

Abstract

The segregation of achiasmate chromosome pairs at meiosis I is not brought about by a single 'distributive system' as previously thought, but rather by two separate mechanisms. One system uses the pairing of proximal heterochromatic sequences to mediate the segregation of achiasmate homologs-an observation that, at long last, defines a function for heterochromatin. The other system facilitates the segregation of heterologous chromosomes, by an as yet undiscovered mechanism.

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