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. 1993 Sep;37(9):2003-6.
doi: 10.1128/AAC.37.9.2003.

Detection and characterization of mupirocin resistance in Staphylococcus aureus

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Detection and characterization of mupirocin resistance in Staphylococcus aureus

D A Janssen et al. Antimicrob Agents Chemother. 1993 Sep.

Abstract

Fourteen mupirocin-resistant Staphylococcus aureus strains were isolated over 18 months; 12 exhibited low-level resistance, while two showed high-level resistance. Highly mupirocin-resistant strains contained a large plasmid which transferred mupirocin resistance to other S. aureus strains and to Staphylococcus epidermidis. This plasmid and pAM899-1, a self-transferable gentamicin resistance plasmid, have molecular and biologic similarities.

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