Detection and characterization of mupirocin resistance in Staphylococcus aureus
- PMID: 8239621
- PMCID: PMC188110
- DOI: 10.1128/AAC.37.9.2003
Detection and characterization of mupirocin resistance in Staphylococcus aureus
Abstract
Fourteen mupirocin-resistant Staphylococcus aureus strains were isolated over 18 months; 12 exhibited low-level resistance, while two showed high-level resistance. Highly mupirocin-resistant strains contained a large plasmid which transferred mupirocin resistance to other S. aureus strains and to Staphylococcus epidermidis. This plasmid and pAM899-1, a self-transferable gentamicin resistance plasmid, have molecular and biologic similarities.
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