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Comparative Study
. 1976 Sep;6(5):471-8.
doi: 10.1111/j.1365-2222.1976.tb01931.x.

The inhibition of allergen induced bronchospasm in man by oral BRL 10833

R Pauwels, H Lamont, M Van der Straeten
Comparative Study

The inhibition of allergen induced bronchospasm in man by oral BRL 10833

R Pauwels et al. Clin Allergy. 1976 Sep.

Abstract

BRL 10833, a nitroindanedione, with DSCG like activity in rat immediate type hypersensitivity, shows good absorption after oral intake in man. The ingestion of 2 and 10 mg BRL 10833/kg body weight provides protection against the immediate type allergen induced bronchoconstriction in patients with bronchial asthma. These results confirm the activity of the drug shown by inhalation.

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