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. 1976 Sep;134(3):297-301.
doi: 10.1093/infdis/134.3.297.

Prompt confirmation of Rocky Mountain spotted fever: identification of rickettsiae in skin tissues

T E Woodward, C E Pedersen Jr, C N Oster, L R Bagley, J Romberger, M J Snyder

Prompt confirmation of Rocky Mountain spotted fever: identification of rickettsiae in skin tissues

T E Woodward et al. J Infect Dis. 1976 Sep.

Abstract

Rickettsia rickettsii were identifiable by the immunofluorescence technique in skin specimens obtained by biopsy on days 4 and 8 of illness from patients with Rocky Mountain spotted fever. The immunofluorescence technique is regarded as a practical means of confirming the diagnosis during the early stages of illness before positive serologic reactions can be obtained.

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