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Case Reports
. 1993 Sep;35(3):171-4.
doi: 10.2334/josnusd1959.35.171.

Histiocytosis X: evidence for a genetic etiology

F Hanapiah  1 , H Yaacob, K S Ghani, A S Hussin
Affiliations
Case Reports

Histiocytosis X: evidence for a genetic etiology

F Hanapiah et al. J Nihon Univ Sch Dent. 1993 Sep.

Abstract

Histiocytosis X is a rare disorder with no particular predilection for race, age or sex. Since its discovery by Hand in 1893, the etiology has remained unknown, although viruses, bacteria and genetic factors have been implicated. Familial occurrence of this disease is very rare, and only a handful of such cases have been reported. The present study adds further evidence to support the influence of genetic factors in the etiology of histiocytosis X.

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