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. 1993 Nov 15;90(22):10421-3.
doi: 10.1073/pnas.90.22.10421.

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function

E Lai  1 , K L Clark, S K Burley, J E Darnell Jr
Affiliations

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function

E Lai et al. Proc Natl Acad Sci U S A. .

Abstract

A family of transcription factors, first identified as hepatocyte nuclear factors (HNF-3 alpha, -3 beta, and -3 gamma) and as a homeotic Drosophila mutant, fork head, has been intensively studied for the past 4 years. Important findings have emerged about the structure of the DNA-binding portion of the proteins as well as biologic discoveries about the diversity of the family and its implied role in early development.

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References

    1. Cell. 1989 May 19;57(4):645-58 - PubMed
    1. Development. 1993 May;118(1):47-59 - PubMed
    1. Cell. 1990 Nov 2;63(3):455-6 - PubMed
    1. Genes Dev. 1990 Aug;4(8):1427-36 - PubMed
    1. Genes Dev. 1991 Mar;5(3):416-27 - PubMed

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