Comparative Study
doi: 10.1006/bbrc.1993.2358.
A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39
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- PMID: 8250863
- DOI: 10.1006/bbrc.1993.2358
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Comparative Study
A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39
Biochem Biophys Res Commun.
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Abstract
We have recently shown that a group of antimicrobial peptides of bovine neutrophils share highly identical pro-sequences. In this paper we report the cDNA sequence of a 172 amino acid residue pig myeloid protein showing a similar pro-sequence of 101 residues. The carboxyl-moiety of the predicted protein is identical to the mature form of the proline- and arginine-rich antibacterial peptide named PR-39, isolated from pig intestine.
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