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Comparative Study
. 1993 Nov 15;196(3):1058-65.
doi: 10.1006/bbrc.1993.2358.

A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39

P Storici  1 , M Zanetti
Affiliations
Comparative Study

A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39

P Storici et al. Biochem Biophys Res Commun. .

Abstract

We have recently shown that a group of antimicrobial peptides of bovine neutrophils share highly identical pro-sequences. In this paper we report the cDNA sequence of a 172 amino acid residue pig myeloid protein showing a similar pro-sequence of 101 residues. The carboxyl-moiety of the predicted protein is identical to the mature form of the proline- and arginine-rich antibacterial peptide named PR-39, isolated from pig intestine.

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