Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1993 Oct;7(5):605-8.
doi: 10.1007/BF00852565.

Genetically engineered kidneys

A S Woolf  1 , L G Fine
Affiliations
Review

Genetically engineered kidneys

A S Woolf et al. Pediatr Nephrol. 1993 Oct.

Abstract

We review the available methods of creating genetically engineered kidneys. These include transgenic technology to introduce novel genes or delete existing genes and methods of gene transfer into the post-natal or adult kidney. The use of such technology has provided insights into renal development and growth and created new animal models of human diseases. Although some of these techniques are of potential use for introducing therapeutically useful gene products into the diseased kidney, many problems remain to be solved before this aim is attained.

PubMed Disclaimer

References

    1. Development. 1992 Mar;114(3):565-72 - PubMed
    1. Exp Nephrol. 1993 Jan-Feb;1(1):49-54 - PubMed
    1. Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4626-30 - PubMed
    1. Nature. 1990 Apr 5;344(6266):541-4 - PubMed
    1. Nephrol Dial Transplant. 1992;7(7):563-72 - PubMed

Publication types

LinkOut - more resources