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. 1993 Oct;31(10):2824-7.
doi: 10.1128/jcm.31.10.2824-2827.1993.

Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS

T Mazzulli  1 , R H Rubin, M J Ferraro, R T D'Aquila, S A Doveikis, B R Smith, T H The, M S Hirsch
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Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS

T Mazzulli et al. J Clin Microbiol. 1993 Oct.

Abstract

We evaluated a rapid immunoperoxidase technique for the detection of cytomegalovirus (CMV) antigenemia in peripheral blood neutrophils of 56 transplant recipients (117 specimens) and 36 persons with AIDS (59 specimens). Antigenemia was 92% sensitive and 98% specific for the detection of clinical CMV infection in transplant recipients and 100% sensitive and 86% specific in persons with AIDS. Overall, CMV antigenemia was a more rapid and sensitive method for the detection of clinical CMV infection than either shell vial culture or conventional tube culture of blood.

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References

    1. Transplant Proc. 1990 Feb;22(1):226-8 - PubMed
    1. J Med Virol. 1989 Oct;29(2):88-93 - PubMed
    1. Rev Infect Dis. 1990 Sep-Oct;12 Suppl 7:S734-44 - PubMed
    1. J Med Virol. 1990 Nov;32(3):160-3 - PubMed
    1. J Clin Microbiol. 1991 May;29(5):1054-5 - PubMed

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