Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS
- PMID: 8253997
- PMCID: PMC266028
- DOI: 10.1128/jcm.31.10.2824-2827.1993
Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS
Abstract
We evaluated a rapid immunoperoxidase technique for the detection of cytomegalovirus (CMV) antigenemia in peripheral blood neutrophils of 56 transplant recipients (117 specimens) and 36 persons with AIDS (59 specimens). Antigenemia was 92% sensitive and 98% specific for the detection of clinical CMV infection in transplant recipients and 100% sensitive and 86% specific in persons with AIDS. Overall, CMV antigenemia was a more rapid and sensitive method for the detection of clinical CMV infection than either shell vial culture or conventional tube culture of blood.
Comment in
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Comparison of cytomegalovirus antigenemia assay with shell vial-indirect immunofluorescence assay for rapid detection of cytomegalovirus in blood.J Clin Microbiol. 1994 Jun;32(6):1619-20. doi: 10.1128/jcm.32.6.1619-1620.1994. J Clin Microbiol. 1994. PMID: 8077419 Free PMC article. No abstract available.
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