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Review
. 1993 Oct;51(10):2598-605.

[Gonadotropes]

[Article in Japanese]
  • PMID: 8254927
Review

[Gonadotropes]

[Article in Japanese]
T Yaginuma. Nihon Rinsho. 1993 Oct.

Abstract

A pulsatile pattern of GnRH release by GnRH pulse generator in the hypothalamus is required for the maintenance of gonadotrope responses, Gn-subunit mRNA production and release of Gn. GnRH causes up-and down-regulation of GnRH receptors and desensitization of Gn-release. Gn-synthesis and release are modulated by gonadal steroid and peptide hormone through the hypothalamus and/or pituitary.

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