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. 1993 Dec 9;366(6455):591-2.
doi: 10.1038/366591a0.

A morphological biosensor for mammalian cells

I Giaever  1 , C R Keese
Affiliations

A morphological biosensor for mammalian cells

I Giaever et al. Nature. .

Abstract

An electrical biosensor is described that can continuously track morphological changes of adherent cells providing quantitative data from both sparse and confluent cultures. The method is capable of detecting vertical motion of cells of the order of 1 nm, much below the resolution of an optical microscope.

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