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. 1993 Sep;28(3):203-7.
doi: 10.1016/0167-8140(93)90059-h.

Nicotinamide and carbogen: major effect on the radiosensitivity of EMT6 and HRT18 tumours

J M Simon  1 , E Lartigau, M Guichard
Affiliations

Nicotinamide and carbogen: major effect on the radiosensitivity of EMT6 and HRT18 tumours

J M Simon et al. Radiother Oncol. 1993 Sep.

Abstract

The effect of nicotinamide and/or carbogen breathing on the response of EMT6 and HRT18 tumours, irradiated in vivo, was evaluated using an in vitro colony assay. In the single dose schedules, the most efficient treatment was carbogen plus nicotinamide compared to air breathing mice. In a fractionated regime carbogen plus nicotinamide increased also response to radiation.

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