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Review
. 1993 Oct;18(10):381-4.
doi: 10.1016/0968-0004(93)90094-4.

Beat the clock: paradigms for NTPases in the maintenance of biological fidelity

S M Burgess  1 , C Guthrie
Affiliations
Review

Beat the clock: paradigms for NTPases in the maintenance of biological fidelity

S M Burgess et al. Trends Biochem Sci. 1993 Oct.

Abstract

Kinetic proofreading is a strategy used by cells to reduce the number of errors made when replicating and expressing genetic information. Recent advances in mRNA splicing suggest a variation on the theme of previously described kinetic proofreading mechanisms, which may apply to other multicomponent assembly processes in the cell.

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