Microfilaments and membranes

Abstract

Microfilaments are intimately involved in many plasma and internal membrane functions. Recent studies of microfilament-membrane linking proteins and non-filamentous myosins implicate microfilaments in diverse functions, including transmembrane signaling and vesicular transport. Evidence from animal and yeast cells suggests that microfilaments are regulated by protein phosphosphorylation, small GTP-binding proteins and associations involving SH3 domains.