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Case Reports
. 1993 Sep;16(8):643-6.
doi: 10.1007/BF03347687.

Insulin-dependent diabetes mellitus associated with Graves' disease and idiopathic hypoparathyroidism

K Yoshioka  1 , A Ohsawa, T Yoshida, S Yokoh
Affiliations
Case Reports

Insulin-dependent diabetes mellitus associated with Graves' disease and idiopathic hypoparathyroidism

K Yoshioka et al. J Endocrinol Invest. 1993 Sep.

Abstract

We report a case of 26-year-old woman with Graves' disease and idiopathic hypoparathyroidism diagnosed at 11 years of age, who subsequently developed insulin-dependent diabetes mellitus (IDDM) at 17 years of age. Treatment with antithyroid agents had failed to control her Graves' disease and her IDDM was unmanageable despite insulin therapy. Surgical intervention was carried out, resulting in an improvement of both her hyperthyroidism and IDDM. This case is the first report of polyglandular autoimmune (PGA) syndrome, presenting the association of IDDM, Graves' disease and idiopathic hypoparathyroidism.

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