[Prognostic factors in primary gastric non-Hodgkin's lymphoma--results of uni- and multivariate analysis]

Abstract

Retrospectively analyzed data of 41 patients with primary gastric non-Hodgkin lymphoma which were all treated by gastric resection are presented with regard to their histopathologic and clinical findings. 87% of the patients were distributed on stage EI and EII (51% high-grade and 49% low-grade lymphoma). R0 resection was achieved in 80% of our cases and in 27% of the cases gastric resection was part of a multimodal therapy. The median follow up of the living patients was 42 months, the overall 5-year survival rate 74%. Tumor stage, extent of surgical resection, histologic grade, tumor site, R0-resection and tumor size showed a significant prognostic influence on survival. The question whether R0 resectable cases benefit from an adjuvant therapy must be answered by further randomized studies.