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Review
. 1993 Oct;3(5):773-8.
doi: 10.1016/0959-4388(93)90152-o.

Human T-cell leukaemia virus type I and neurological disease

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Review

Human T-cell leukaemia virus type I and neurological disease

C R Bangham. Curr Opin Neurobiol. 1993 Oct.

Abstract

Tropical spastic paraparesis is thought to be caused either directly by human T-cell leukaemia virus type I (HTLV-1), or by the immune response to the virus. Recent work has identified differences between tropical spastic paraparesis patients and healthy carriers of HTLV-I, both in the virus and in the host's T-cell response to the virus. These differences may provide clues to the pathogenesis of tropical spastic paraparesis.

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