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Comparative Study
. 1993 Nov 25;21(23):5289-93.
doi: 10.1093/nar/21.23.5289-a.

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins

B Hu  1 , R Burkhart, D Schulte, C Musahl, R Knippers
Affiliations
Free PMC article
Comparative Study

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins

B Hu et al. Nucleic Acids Res. .
Free PMC article

Abstract

Monospecific antibodies against an oligopeptide, conserved among the Mcm class of yeast replication proteins, were used to screen a human cDNA library. Eight of the isolated cDNA clones have the potential to code for sections of proteins with high sequence similarities to the yeast proteins Mcm3 and Cdc46 from Saccharomyces cerevisiae and Cdc21 from S. pombe. Our results establish a novel and highly conserved family of nuclear proteins in mammalian cells.

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References

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