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Comparative Study
. 1978 Nov 25;2(8100):1126-7.
doi: 10.1016/s0140-6736(78)92278-x.

Significance of HLA-D/DR matching in renal transplantation

D Albrechtsen, A Flatmark, J Jervell, S Halvorsen, B G Solheim, E Thorsby
Comparative Study

Significance of HLA-D/DR matching in renal transplantation

D Albrechtsen et al. Lancet. .

Abstract

A low mixed-lymphocyte-culture response, indicating matching for HLA-D, was associated with a relatively good chance of graft survival in 62 recipients of renal transplants from living relatives mismatched for one or two HLA A and/or B antigens. In 96 cadaveric transplants prospectively typed for HLA-DR antigens, compatibility for these antigens improved the prognosis, irrespective of matching for HLA A and B antigens. In cadaveric transplants, a positive B-cell cross-match test before transplantation tended to predict inferior graft survival.

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