[Aetiology of dupuytren's contracture (author's transl)]
- PMID: 827084
- DOI: 10.1007/BF00429717
[Aetiology of dupuytren's contracture (author's transl)]
Abstract
Regarding experimental data on the multi-factorial reduction of the thermostability of collagen, the following sequence of the mechanism of Dupuytren's contracture is discussed: 1. Hereditary or acquired weakness of fibres of the palmar fascia 2. Further disturbance of the physical property of collagen by the cumulative effects of mechanical, i.e. traumatic, influence. 3. By this means an induced stepwise shrinkage of released fascial fibres in body temperature. 4. Stabilisation of the shortening (contracture) by development of collagen. This hypothesis is supported by histological, polarizing-microscopic, electron-microscopic and chemical results.
Similar articles
-
Biochemical changes in the collagen of the palmar fascia in patients with Dupuytren's disease.J Bone Joint Surg Am. 1981 Jun;63(5):787-97. J Bone Joint Surg Am. 1981. PMID: 7240301
-
A study of Dupuytren's tissue with the scanning electron microscope.J Hand Surg Am. 1981 Sep;6(5):482-92. doi: 10.1016/s0363-5023(81)80109-8. J Hand Surg Am. 1981. PMID: 7276480
-
The collagen changes of Dupuytren's contracture.J Hand Surg Br. 1991 Aug;16(3):263-6. doi: 10.1016/0266-7681(91)90050-x. J Hand Surg Br. 1991. PMID: 1960490
-
The role of the fibroblast in Dupuytren's contracture.Hand Clin. 1991 Nov;7(4):669-80; discussion 681. Hand Clin. 1991. PMID: 1769989 Review.
-
[The pathobiochemistry of Dupuytren's contracture].Chir Narzadow Ruchu Ortop Pol. 2009 Mar-Apr;74(2):68-73. Chir Narzadow Ruchu Ortop Pol. 2009. PMID: 19514484 Review. Polish.
Cited by
-
Myofibroblast-like cells in human anterior capsular cataract.Virchows Arch A Pathol Anat Histopathol. 1984;404(4):393-401. doi: 10.1007/BF00695223. Virchows Arch A Pathol Anat Histopathol. 1984. PMID: 6437072
-
[Banded filamentous associates in the intra- and extracellular space in connection with collagen degradation (author's transl)].Virchows Arch A Pathol Anat Histol. 1977 Sep 28;375(3):185-96. doi: 10.1007/BF01102987. Virchows Arch A Pathol Anat Histol. 1977. PMID: 198946 German.
-
Vascular thermocoagulation-perivascular nerve lesions. An ultrastructural report on the choice between monopolar and bipolar electrocoagulation.Acta Neurochir (Wien). 1988;92(1-4):123-31. doi: 10.1007/BF01401982. Acta Neurochir (Wien). 1988. PMID: 3407466
-
Palmar fibromatosis (Dupuytren's contracture). Ultrastructural and enzyme histochemical studies of 43 cases.Virchows Arch A Pathol Anat Histopathol. 1984;405(1):41-53. doi: 10.1007/BF00694924. Virchows Arch A Pathol Anat Histopathol. 1984. PMID: 6150573